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Dietary cholesterol worsens inflammation, sickness in mice with influenza

URBANA, Ill. – New research from the University of Illinois suggests high levels of dietary cholesterol make mice sicker when infected with influenza. The study is the first to link cholesterol in the diet with exacerbation of a viral infection.

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Illinois program turns cowgirl dreams into livestock research reality

URBANA, Ill. – The moment 4-year-old Sarah Graham sat in a saddle for the first time, she announced she wanted to be a cowgirl. For the suburban Chicago preschooler, it was an unlikely dream. But it stuck.

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Avocado meal, a novel fiber source for dogs

URBANA, Ill. – When avocados were first recognized as a nutrient-dense superfood for humans, consumption skyrocketed. Today, consumers buy and eat the fresh fruit (hello, avocado toast), purchase pre-packaged guacamole, cook with avocado oil, and more.

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Colorectal cancer in context: How the food environment affects the gut

URBANA, Ill. – Colorectal cancer is expected to claim more than 52,000 American lives in 2022, and if this year is like most others, Black Americans will bear the brunt of the disease. To understand the disparity in context, University of Illinois researchers looked at the intersection of bile acids, gut microbes, racial identity, and neighborhood food environment in the development of colorectal cancer.

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New tests and treatments developed in mice for pulmonary fibrosis

URBANA, Ill. – Scientists at the University of Illinois at Urbana-Champaign and Mie University in Japan have developed monoclonal antibodies that prevent lung cell death in mouse models for idiopathic pulmonary fibrosis (IPF) and acute respiratory disease syndrome (ARDS). The advance, along with new, non-invasive diagnostic tools presented in the same study, could be a critical step in treating the deadly diseases, for which few effective therapies currently exist.

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Quantum dots shine bright to help scientists see inflammatory cells in fat

URBANA, Ill. -- To accurately diagnose and treat diseases, doctors and researchers need to see inside bodies. Medical imaging tools have come a long way since the humble x-ray, but most existing tools remain too coarse to quantify numbers or specific types of cells inside deep tissues of the body. 

Quantum dots can do that, according to new research in mice from the University of Illinois.

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Team uses MRI to image epigenetics in the brain

CHAMPAIGN, Ill. — A multidisciplinary team at the University of Illinois Urbana-Champaign has devised a new approach to 3D imaging that captures DNA methylation, a key epigenetic change associated with learning in the brain. The scientists say their proof-of-concept study in pigs will easily translate to humans, as the new method relies on standard MRI technology and biological markers already in use in human medicine.

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5 Questions: Reproductive biologist thriving at the intersection of biomedical science and agriculture

This week’s 5 Questions Friday features Matthew Dean, assistant professor in the Department of Animal Sciences. Dean's group studies the female reproductive system, with the goal of improving fertility in both humans and livestock.

What motivates you in your work?

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Overweight dogs respond well to high-protein, high-fiber diet

CHAMPAIGN, Ill. — A study of overweight dogs fed a reduced calorie, high-protein, high-fiber diet for 24 weeks found that the dogs’ body composition and inflammatory markers changed over time in ways that parallel the positive changes seen in humans on similar diets. The dogs achieved a healthier weight without losing too much muscle mass, and their serum triglycerides, insulin and inflammatory markers all decreased with weight loss.

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Endangered deer's prion gene could protect it from chronic wasting disease

URBANA, Ill. – China’s Père David’s deer was nearly gone in the late 1800s. Just 18 deer – the very last of their kind – were brought into captivity after the rest had been hunted to extinction. When 11 of the deer reproduced, the species had a chance. Today, after centuries of reintroductions and breeding under human care, the population sits at around 3,000.

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